Frequently Asked Questions

TAFINLAR + MEKINIST

How long do I take TAFINLAR + MEKINIST?

Keep taking TAFINLAR + MEKINIST for as long as your health care provider tells you. Tell your health care provider if you have any side effect that bothers you or that does not go away.

What if I miss a dose?

If you miss a dose of TAFINLAR or MEKINIST, take it as soon as you remember. But if you miss a dose of TAFINLAR, and it is within 6 hours of your next scheduled dose, or if you miss a dose of MEKINIST, and it is within 12 hours of your next scheduled dose, just take your next dose at the regular time. Do not make up for the missed dose.

What can I do about side effects?

Tell your health care provider if you have any side effect that bothers you or that does not go away. Your health care provider may change, temporarily interrupt, or decrease your dose of TAFINLAR and/or MEKINIST during your treatment to help manage side effects. Depending on side effect and severity, your health care provider may need to discontinue your treatment. If you have any questions about your treatment, talk to your health care provider.

Do I need to take every dose?

It is important to take TAFINLAR + MEKINIST exactly as your health care provider tells you. Do not change your dose or stop taking TAFINLAR or MEKINIST unless your health care provider tells you.

How do I store my TAFINLAR and MEKINIST?

Store TAFINLAR at room temperature, between 68°F to 77°F (20°C-25°C)
Store MEKINIST in the refrigerator between 36°F to 46°F (2°C-8°C)
Keep TAFINLAR and the drying agent (desiccant) in the original bottle to protect from moisture
Keep MEKINIST dry and away from moisture and light
The bottle of MEKINIST contains a desiccant packet to help keep your medicine dry. Do not throw away the desiccant packet
Keep MEKINIST in its original bottle. Do not place tablets in a pill box
Safely throw away MEKINIST that is out of date or no longer needed
Keep TAFINLAR, MEKINIST, and all medicines out of the reach of children

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Important Safety Information

TAFINLAR and MEKINIST may cause serious side effects, including:

Risk of new cancers. TAFINLAR, when used in combination with MEKINIST, may cause a type of skin cancer called cutaneous squamous cell carcinoma, keratoacanthoma, basal cell carcinoma, or melanoma. Talk with your health care provider about your risk for these cancers. Check your skin and tell your health care provider right away about any skin changes, including a new wart, skin sore, or reddish bump that bleeds or does not heal, or a change in size or color of a mole.

Your health care provider should check your skin before you start treatment, and every 2 months while on treatment, to look for any new skin cancers. Your health care provider should continue to check your skin for 6 months after you stop taking TAFINLAR and MEKINIST.

Approved Uses

TAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat people with a type of skin cancer called melanoma:

that has spread to other parts of the body (metastatic) or cannot be removed by surgery (unresectable), and
that has a certain type of abnormal “BRAF” (V600E or V600K mutation-positive) gene

TAFINLAR and MEKINIST are prescription medicines that can be used in combination to help prevent melanoma that has a certain type of abnormal “BRAF” gene from coming back after the cancer has been removed by surgery.

Click or scroll to see IMPORTANT SAFETY INFORMATION AND APPROVED USES

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