If you miss a dose of TAFINLAR or MEKINIST, take it as soon as you remember. But if you miss a dose of TAFINLAR, and it is within 6 hours of your next scheduled dose, or if you miss a dose of MEKINIST, and it is within 12 hours of your next scheduled dose, just take your next dose at the regular time. Do not make up for the missed dose.

Tell your health care provider if you have any side effect that bothers you or that does not go away. Your health care provider may change, temporarily interrupt, or decrease your dose of TAFINLAR and/or MEKINIST during your treatment to help manage side effects. Depending on side effect and severity, your health care provider may need to discontinue your treatment. If you have any questions about your treatment, talk to your health care provider.

It is important to take TAFINLAR + MEKINIST exactly as your health care provider tells you. Do not change your dose or stop taking TAFINLAR or MEKINIST unless your health care provider tells you.

• Store TAFINLAR at room temperature, between 68°F to 77°F (20°C-25°C)

• Store MEKINIST in the refrigerator between 36°F to 46°F (2°C-8°C)

• Keep TAFINLAR and the drying agent (desiccant) in the original bottle to protect from moisture

• Keep MEKINIST dry and away from moisture and light

• The bottle of MEKINIST contains a desiccant packet to help keep your medicine dry. Do not throw away the desiccant packet

• Keep MEKINIST in its original bottle. Do not place tablets in a pill box

• Safely throw away MEKINIST that is out of date or no longer needed

• Keep TAFINLAR, MEKINIST, and all medicines out of the reach of children