Side Effects | TAFINLAR + MEKINIST for BRAF V600E mNSCLC

Side effects of TAFINLAR + MEKINIST

Serious side effects
As with many medications, you may experience some side effects while taking TAFINLAR + MEKINIST in combination. Below are possible side effects of treatment.

Taking TAFINLAR + MEKINIST may cause serious side effects, including:

New skin cancers, including cutaneous squamous cell carcinoma, keratoacanthoma, basal cell carcinoma, or melanoma	Bleeding problems
Inflammation of the intestines or tears (perforation) of the stomach or intestines	Blood clots
Heart problems, including heart failure	Eye problems
Lung or breathing problems	Fever
Serious skin reactions	Increased blood sugar (hyperglycemia)
Healthy red blood cells to break down too early in people with glucose-6-phosphate dehydrogenase deficiency	New or worsening high blood pressure (hypertension)
May increase the risk of a type of overactivity of the immune system (hemophagocytic lymphohistiocytosis) that can cause fever, swollen glands, bruising, or skin rash	Low sperm counts
Fertility problems

The most common side effects of TAFINLAR, in combination with MEKINIST, when used in patients with NSCLC include:

Fever	Tiredness	Nausea
Vomiting	Diarrhea (call your health care provider if you get severe diarrhea)	Dry skin
Decreased appetite	Rash	Swelling of the face, arms, and legs
Chills	Bleeding	Cough
Shortness of breath

Talk to your health care provider about your side effects. These are not all the possible side effects of TAFINLAR + MEKINIST. Be sure to tell your health care provider about how you’re feeling or if you have any concerns about your treatment.

Next: Side Effect Management >

Side effects of TAFINLAR + MEKINIST

Frequently Asked Questions

Important Safety Information

Approved Uses